A number of effective medications are available for the treatment of acute headaches, which provide rapid relief, and thus, a significant improvement in the quality of life of affected patients. However, if these drugs are taken too frequently, there is a risk of developing medication overuse headache. This means that the medication, which is actually taken to relieve the headache, causes an increase in the headache and a vicious circle ensues, resulting in a further increase in medication consumption. Medication for acute headaches should therefore not be taken more often than an average of 8 days per month. If a medication overuse headache is suspected, treatment at a specialized center is strongly recommended.