The brain is the most fascinating and ingenious gift we have received.
We are interested in brain diseases of fetuses, children and adolescents, and study tumours and neurodevelopmental disorders/developmental neuropathologies.
Pediatric brain tumours are the most common solid tumours and the most common cause of cancer death in childhood. Our research focuses on molecular diagnostic and prognostic markers of pediatric brain tumours. We are particularly interested in the tumour microenvironment and brain development and their role in tumour origin.
Developmental malformations of the brain comprise a wide range of different disorders. We correlate pre- and postnatal MRI images with morphological phenotypes and genetic alterations for a better understanding of these disabling diseases.
I am Principal Investigator and neuropathologist at the Division of Neuropathology and Neurochemistry. My research is focused on the deep phenotypic characterization of malignant brain tumors such as glioblastoma or primary CNS lymphoma. We typically study population-scale cohorts, which we recruit through a disease registry and the local neurobiobank, and bring together multiplatform imaging phenotypes with molecular tumor profiles. We are particularly interested in the longitudinal tumor evolution including clonal outgrowth as well as the unique environment of aging brains.
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