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Epileptology

Research Groups and Laboratories

In epilepsy diagnostics, we are particularly concerned with focal cortical dysplasias, Ammon's horn sclerosis and epilepsy-associated tumors. Together with colleagues from other disciplines, complex cases are discussed as part of interdisciplinary epilepsy boards in order to achieve optimal therapy planning.

Research Group Gelpi

Neurodegenerative diseases including prions, neuropathology, epilepsy pathology

 

Priv.-Doz.in Dr.in Ellen Gelpi-Mantius, PhD
ellen.gelpimantius@meduniwien.ac.at

Contact Lab:
Priv.-Doz. Dr. Günther Regelsberger

guenther.regelsberger@meduniwien.ac.at

Contact Genetics:
Univ.-Prof. Dr. Thomas Ströbel

thomas.stroebel@meduniwien.ac.at

Research Focus:

  • Our focus is on deepening the neuropathological substrate of neurodegenerative diseases, especially the detection of early tissue changes at the cellular level, propagation of the pathology and molecular basis of neurodegeneration; We support the development of biomarkers.

  • Austrian Reference Center for the Recording and Documentation of Human Prion Diseases (ÖRPE): On behalf of the Federal Ministry of Social Affairs, Health, Care and Consumer Protection.

Methods:

  • Neuropathology: Conventional histological stains, immunohistochemistry, electron microscopy, immunofluorescence/confocal microscopy; molecular biological including genetic studies; Neurochemistry: ELISA, RTQuIC.

Keywords:

  • neurodegenerative diseases; neuropathology; prion disorders; RTQuIC; tau; synuclein; TDP-43; FUS

Research Group Haberler

Pediatric brain tumors, CNS malformations, epilepsy-pathology

 

Univ.-Prof.in Dr.in Christine Haberler
christine.haberler@meduniwien.ac.at

ORCID

Research Focus:

  • The brain is the most fascinating and ingenious gift we have received.

  • We are interested in brain diseases of fetuses, children and adolescents, and study tumours and neurodevelopmental disorders/developmental neuropathologies.
  • Pediatric brain tumours are the most common solid tumours and the most common cause of cancer death in childhood. Our research focuses on molecular diagnostic and prognostic markers of pediatric brain tumours. We are particularly interested in the tumour microenvironment and brain development and their role in tumour origin.
  • Developmental malformations of the brain comprise a wide range of different disorders. We correlate pre- and postnatal MRI images with morphological phenotypes and genetic alterations for a better understanding of these disabling diseases.

Alumni:

  • Asuka Araki

  • Bernadette Becsi

  • Johannes Gojo

  • Sabine Kaindl

  • Dominik Kirchhofer

  • Philippe Muller

  • Harald Stefanits

  • Anna Walter