We are interested in the identification of genetic susceptibility factors for neurological diseases. Particularly, our focus lies on Parkinson´s disease and Multiple Sclerosis. Both diseases have a significant genetic component. In the last 20 years a number of genetic susceptibility factors were found which contribute to disease development. However, the loci found so far cannot explain the observed heritability. We are currently performing Next generation “Exome sequencing” in familial Parkinson´s disease and Multiple Sclerosis patients to find highly penetrant genes.
Assoc.Prof. Dr. Alexander Zimprich